Apnea of prematurity (AOP) affects the majority of preterm infants and increases inversely with gestational age at birth. The most affected are extremely premature births, 2% of births, reaching 2.68 million children per year worldwide (Eichenwald, Pediatrics 2019).
The concern with these immature breathing patterns is that they are accompanied by intermittent hypoxia (IH) events. Sequential and repetitive exposure triggers inflammatory reactions and the production of free radicals, which contribute to the pathogenesis of cardiovascular and neurocognitive alterations, causing moderate to severe sequelae in 40-50%, and even death in up to 10%. -20% (between approximately 268,000 and 536,000) (Di Fiore, Respir Physiol Neurobiol 2019) .
PIMUN It is a medical device to reduce AOP, through kinesthetic stimulation on the dorsum of the chest with a pulsatile pattern that simulates an age-appropriate rhythm and constantly encourages breathing in the NB. Its use is intended to be used by 500-2000g NBs in neonatology units. This device we have called PIMUN (fantasy name). The advances that we have are:
- A pneumatic system that emits air pulses with adjustable frequency (Controller)
- A built-in inflatable/deinflatable chamber (actuator or simulator)
- A T-shirt to fix the actuator
María Jesús Álvarez
Pontificia Universidad Católica de Chile